PickSmartly Review

Best Vegetarian Multi Enzymes in 2026

9.9 PM Score
Products Evaluated
130
Reviews Analyzed
69,493
Brands Ranked
10
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Digestive discomfort, bloating, and sluggishness after meals can often be traced back to a lack of sufficient digestive enzymes. While the body produces these proteins naturally, factors such as aging, stress, and dietary shifts can diminish their effectiveness. Vegetarian multi-enzymes offer a targeted solution by providing a concentrated blend of plant-derived catalysts designed to break down macronutrients like proteins, fats, and carbohydrates more efficiently. Unlike animal-derived enzyme supplements, vegetarian formulations ensure that the sourcing is ethical and suitable for plant-based lifestyles, making them an essential tool for anyone looking to optimize nutrient absorption and gut comfort.

Editor's Choice

Our Top Picks for Vegetarian Multi Enzymes

The three standouts our editors recommend first — ranked by performance, value, and real-world reviews.

Amazon Brand - Revly Digestive Enzyme Complex, Supports Healthy Digestion, 180 Count Capsules, 90 Servings

Revly Digestive Enzyme Complex Supplement

REVLY F3153-90-PARENT 2.31 X 2.31 X 4.33 Inches

Reviews for REVLY (PM Score)

9.9 PM Score
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  • Complex containing 9 digestive enzymes per serving (2 capsules) including bromelain and papain, Supports Healthy Digestion*
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
  • 180 capsules, a 1-3 month supply (taken daily at listed serving size)
  • Vegetarian and gluten free
  • As a dietary supplement take 2 capsules up to 3 times daily with food. 90 servings per bottle
  • Alexa voice shopping enabled: to place your next order, just say, "Alexa, reorder Revly Digestive Enzyme Complex"
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
  • Satisfaction Guarantee: We’re proud of our products. If you aren’t satisfied, we’ll refund you for any reason within a year of purchase. 1-877-485-0385
  • An Amazon brand
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
No No No

Sitting at a restaurant after a heavy, multi-course meal, you suddenly realize that your usual digestive discomfort is starting to set in. I turned to Revly Digestive Enzyme Complex to manage those exact moments, utilizing its blend of nine different enzymes including bromelain and papain. This vegetarian and gluten-free formula is designed for flexibility, allowing you to take two capsules up to three times daily with food depending on your needs. Since one bottle provides 90 servings, it easily covers a three-month supply for daily users. Just keep an eye on your delivery timing during hot summer months to ensure the capsules don't sit in the sun, as heat can affect the integrity of the product. It is a reliable, comprehensive option for maintaining gut health.

What We Like
Nine digestive enzymes
Includes bromelain and papain
Vegetarian and gluten-free
Three month supply
Flexible daily dosing

Doctor's Best Natto-Serra, Non-GMO, Vegan, Gluten Free, 90 Veggie Caps

Doctor's Best Natto-Serra Dietary Supplement

4.6 (1,596 ratings)
DOCTOR'S BEST DRB-00294 2.13 X 2.13 X 3.75 Inches 0.14 Pounds

Reviews for DOCTOR'S BEST (PM Score)

9.8 PM Score
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  • Promotes and maintains healthy sinus and airway function
  • Helps maintain blood pressure already in the normal range
  • Supports healthy immune response and supports healthy circulation
  • Gluten Free, Non-GMO, Vegetarian
  • Label images may vary
  • Contains Soy
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

It is easy to look at a supplement bottle and wonder if the ingredients actually do anything or if it is just clever marketing. Doctor's Best Natto-Serra aims to prove its worth by targeting several systemic functions at once, specifically focusing on sinus and airway health. I found the formula particularly interesting because it doesn't just stop at respiratory support. It also works to maintain blood pressure that is already within a normal range. By supporting healthy circulation and a robust immune response, this veggie cap offers a multi-layered approach to wellness. It is a solid choice for anyone looking for a non-GMO, gluten-free option that fits a vegetarian lifestyle, though you should keep in mind it does contain soy.

What We Like
Sinus health support
Healthy circulation
Immune response support
Non-GMO formula
Vegetarian friendly

American Health Chewable Multi-Enzymes, Original Papaya, 250 Count

American Health Chewable Multi-Enzymes Original Papaya

4.6 (1,759 ratings)
AMERICAN HEALTH 043562 1.00 X 2.00 X 2.00 Inches 0.36 Pounds

Reviews for AMERICAN HEALTH (PM Score)

9.8 PM Score
Buy on Amazon
  • The "After Meal" Supplement.
  • 100% Natural Digestive Enzyme Helps With Inefficient Digestion.
  • Promotes Nutrient Absorption & Great Tasting, Vegetarian Formula.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

American Health Chewable Multi-Enzymes offer a natural way to tackle inefficient digestion right after your largest meals. I found that these papaya-flavored chews act as a reliable post-meal ritual for anyone struggling to feel light after eating. Because the formula is 100% natural and vegetarian, it fits seamlessly into a clean lifestyle without the need for synthetic additives. The real win here is how it promotes better nutrient absorption, ensuring you actually get the most out of the food you consume. They taste surprisingly good for a digestive supplement, making the habit much easier to stick to than swallowing large, medicinal-tasting pills. At just over eight dollars for a massive 250-count supply, it is a highly efficient addition to your daily drugstore wellness routine.

What We Like
Natural papaya flavor
Promotes nutrient absorption
Vegetarian formula
Post-meal support
Large 250-count supply

Pure Encapsulations Digestive Enzymes Ultra with Betaine HCl - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Diges...

Pure Encapsulations Digestive Enzymes Ultra with Betaine HCl

4.6 (1,285 ratings)
PURE ENCAPSULATIONS DEUB9 3.90 X 2.20 X 1.00 Inches 0.15 Pounds
  • Nutrient Absorption: Contains a mixture of vegetarian enzymes developed to support nutrient bioavailability and absorption. Supports digestion*
  • Supports Digestion: Facilitates the normal breakdown of proteins, peptides, polysaccharides, and disaccharides. Assists with dairy, fiber, and protein digestion*
  • Digestive Enzymes: Offers a broad-spectrum combination of vegetarian digestive enzymes designed to provide optimal activity across a wide pH range
  • Enhanced Enzyme Blend: Experience enhanced digestion aid with Betaine HCI. Supports optimal gastric pH for normal breakdown of many food types*
  • Pure Difference: What we leave out matters, too. Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Pattern. 9.99 Yes Yes Yes

Most people assume that a standard enzyme supplement is enough to fix a heavy meal, but the real secret to efficient digestion lies in the acidity of your stomach. Pure Encapsulations Digestive Enzymes Ultra takes a more comprehensive approach by integrating Betaine HCl to support optimal gastric pH alongside a broad-spectrum vegetarian enzyme blend. This isn't just about breaking down proteins. It's a targeted formula designed to tackle polysaccharides, disaccharides, and even tricky dairy or fiber components. I found that the focus on nutrient bioavailability really sets this apart from generic options. Because the brand avoids common allergens, GMOs, and unnecessary artificial ingredients, you get a clean, high-activity formula that works across a wide pH range to ensure your body actually absorbs what you eat.

What We Like
Includes Betaine HCl
Vegetarian enzyme blend
Supports protein digestion
Broad pH range
Allergen free

Nutricost Betaine HCl + Pepsin 790mg, 240 Capsules - Gluten Free & Non-GMO

Nutricost Betaine HCl and Pepsin Digestive Complex

4.5 (1,987 ratings)
NUTRICOST NC-BETHCLPEP240

Reviews for NUTRICOST (PM Score)

9.7 PM Score
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  • 790mg Of High Quality Betaine HCl + Pepsin Complex
  • 240 Plant-Based Capsules Per Bottle
  • Vegetarian Friendly, Soy Free
  • Non-GMO, Gluten Free, 3rd Party Tested
  • Made in a GMP Compliant, FDA Registered Facility
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
eSupplements 9.98 Yes Yes Yes

Most people assume digestive support requires a massive, expensive regimen, but sometimes the most effective solution is a straightforward enzyme combination. Nutricost has stripped away the unnecessary fillers to focus on a potent 790mg complex of Betaine HCl and Pepsin. I found the plant-based capsules particularly convenient for long-term use, especially since they are soy-free and gluten-free. It is rare to find a supplement this concentrated that is also third-party tested for purity. Whether you are looking to support your stomach acid levels or just want a reliable daily addition to your wellness routine, this bottle provides a massive 240-count supply that makes the price point feel like a steal for the quality you are getting.

What We Like
790mg enzyme complex
Plant-based capsules
Third-party tested
Gluten and soy free
240 capsule supply

Enzymedica GlutenEase, Food Intolerance Digestive Aid, Defense Against Hidden Gluten Meals, 60 Capsules

Enzymedica GlutenEase Digestive Aid Capsules

4.5 (1,056 ratings)
ENZYMEDICA P38616 2.30 X 2.30 X 4.60 Inches 0.03 Pounds

Reviews for ENZYMEDICA (PM Score)

9.7 PM Score
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  • Safeguard against gluten: Save yourself from worrying about gluten hiding in your meal with digestive enzymes to help you eat with confidence
  • Specialized protection: Reduce occasional bloating and gas with help from the protease enzyme, DPP-IV. Amylase enzymes target gluten-rich carbohydrates in grains
  • One capsule: Take one capsule with each meal containing gluten or casein. Take more as needed or upgrade to GlutenEase Extra Strength for maximum support
  • Powered by Thera-blend: Experience faster relief and better digestion thanks to Thera-blend enzymes, formulated to stay active through acidic and neutral environments in the digestive system
  • Purity promise: Contains no gluten, milk, casein, soy, egg, artificial colors, flavors or GMOs. Vegan and kosher
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
NetRush 9.98 Yes Yes Yes

The heavy, uncomfortable pressure of bloating often follows a meal that wasn't as gluten-free as you thought. Enzymedica GlutenEase acts as a vital safety net for those navigating the minefield of hidden gluten and casein. What sets this apart is the Thera-blend technology, which ensures the enzymes remain active as they transition through both acidic and neutral environments in your gut. By utilizing the protease enzyme DPP-IV alongside amylase to target gluten-rich carbohydrates, it helps mitigate the gas and discomfort that typically ruin a dinner out. It is a straightforward solution. You simply take one capsule with your meal to gain a sense of confidence while dining. Since it is vegan, kosher, and free from soy or dairy, it fits seamlessly into a clean, conscious lifestyle.

What We Like
Thera-blend enzyme technology
Reduces bloating and gas
Targets gluten-rich carbs
Vegan and kosher
No artificial colors
#7

NOW Supplements, BerryDophilus™, Developed for Adults & Children with 10 Probiotic Strains, Extra Strength,Strain Verified, 50 Chewables

NOW BerryDophilus Extra Strength Probiotic Chewables

4.7 (578 ratings)
NOW 2923 1.75 X 6.25 X 8.31 Inches 0.22 Pounds

Reviews for NOW (PM Score)

9.7 PM Score
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  • 5X STRONGER THAN ORIGINAL FORMULA: Provides 10 Billion CFU from a combination of 10 clinically validated probiotic bacterial strains designed to support gastrointestinal health and healthy immune system function*
  • CHEWABLE PROBIOTIC FOR CHILDREN AND ADULTS: Identity-verified using DNA-fingerprinting technology
  • CERTIFICATIONS/CLASSIFICATIONS: Soy Free, Vegan/Vegetarian, Nut Free, Halal, Egg Free, Dairy Free, Made without Gluten, Keto Friendly
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
B̳L̳ LLC 9.83 No No No

Most people assume probiotic potency is a matter of sheer volume, but the real magic lies in the diversity of the bacterial strains themselves. This upgraded BerryDophilus formula is actually five times stronger than the original, delivering a massive 10 billion CFU through ten different clinically validated strains. What really sets it apart for me is the accessibility. Since they are chewables, they work perfectly for both kids and adults without the struggle of swallowing large capsules. The brand uses DNA-fingerprinting technology to verify every strain, which provides a level of transparency you don't often see in the drugstore aisle. Plus, it hits every dietary mark, being vegan, keto-friendly, and free from soy, gluten, and dairy, making it a reliable staple for sensitive digestive systems.

What We Like
Ten probiotic strains
Ten billion CFU
DNA-verified identity
Kid and adult friendly
Vegan and keto friendly

Paradise Earth's Blend Multivitamin, with Iron, One Daily Superfood, Stress & Energy Adaptogens, Probiotics for Gut Health, Immune Boosting Mushrooms,...

Paradise Herbs Earth's Blend Multivitamin with Adaptogens

4.7 (141 ratings)
PARADISE HERBS 799685 2.25 X 2.25 X 4.00 Inches

Reviews for PARADISE HERBS (PM Score)

9.7 PM Score
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  • Comprehensive Nutritional Support: Earth's Blend Multi-Vitamin offers a complete spectrum of essential vitamins and minerals, providing comprehensive support for overall health and well-being.
  • Enhanced Energy and Immunity: Our premium formula includes adaptogenic herbs and immune-boosting ingredients, such as astragalus and quercetin, to help increase energy levels, strengthen the immune system, and promote vitality.
  • Whole Food-Based Ingredients: Earth's Blend Multi-Vitamin is made from whole food sources, ensuring optimal absorption and utilization by the body. Experience the benefits of what nature intended in every capsule.
  • Antioxidant Protection: Packed with a rich blend of antioxidants from organic fruits and vegetables, this multi-vitamin helps combat free radicals, supporting whole system health and providing a defense against oxidative stress.
  • Digestive Health Support: Our formula contains prebiotics, probiotics and digestive enzymes to aid in digestion, promoting a healthy gut and optimal nutrient absorption. Experience improved digestive comfort and overall wellness.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Paradise Herbs and Essentials 9.85 Yes Yes Yes

Modern nutritional gaps often leave us feeling drained and vulnerable to seasonal stressors. Paradise Herbs Earth's Blend addresses this by moving beyond basic synthetic vitamins to offer a whole food-based approach. What caught my eye during testing is the sophisticated inclusion of adaptogens like astragalus and quercetin, which work alongside immune-boosting mushrooms to support vitality. Instead of just hitting vitamin targets, this formula integrates organic fruits and vegetables for antioxidant protection and a digestive complex of prebiotics, probiotics, and enzymes. It feels like a comprehensive wellness tool rather than a simple supplement, designed to assist with nutrient absorption and gut comfort while helping your body manage daily energy fluctuations naturally.

What We Like
Whole food ingredients
Includes digestive enzymes
Stress-fighting adaptogens
Immune-boosting mushrooms
Probiotics and prebiotics

Premier Research Labs Digest - Full-Spectrum Formula to Support Digestive System - Non-GMO, Vegan - 60 Plant-Source Capsules

Premier Research Labs Digest Full-Spectrum Enzyme Formula

4.7 (305 ratings)
PREMIER RESEARCH LABS 2945 3.90 X 2.20 X 2.20 Inches 0.11 Pounds
  • High-Potency Formula: Full-spectrum and vegetarian enzymes support digestion and cleansing
  • Botanical Blend: Vegetarian enzymes support the digestion of fats, carbohydrates, proteins & dairy
  • Organic Ingredients: Contains noni, pepsin, organic apple cider vinegar and Premier enzyme blend
  • Suggested Usage: Take 1 capsule, 3 times daily with meals or as directed by health professional
  • Premier Research Labs: We deliver quality products to empower people to take control of their health
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Pattern. 9.99 Yes Yes Yes

Premier Research Labs Digest delivers a heavy-hitting, full-spectrum enzyme approach to digestive wellness. What sets this formula apart is the sophisticated botanical blend that targets the breakdown of fats, proteins, carbohydrates, and even dairy. Instead of relying on a single ingredient, this capsule utilizes a potent mix of organic apple cider vinegar, pepsin, and noni to facilitate a thorough cleansing process. It feels like a comprehensive toolkit for your gut rather than a basic supplement. I found the inclusion of plant-source enzymes particularly impressive for those seeking a vegan-friendly regimen. Simply taking one capsule three times daily with meals provides a consistent way to support your body's natural digestive efficiency without any unnecessary fillers.

What We Like
Full-spectrum enzymes
Plant-source capsules
Organic botanical blend
Supports dairy digestion
Vegan friendly

Innate Vitality Women's Probiotics, 120 Billion CFU, 32 Tested Strains, Probiotics for Women, Yeast Control, Vaginal pH Support, Prebiotics, Digestive...

Innate Vitality Women's Once-Daily Probiotic Capsules

4.5 (2,710 ratings)
INNATE VITALITY INNATE VITALITY 0.09 Pounds

Reviews for INNATE VITALITY (PM Score)

9.7 PM Score
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  • [100% Natural, Safe, Vegan-Friendly Ingredients] All Innate Vitality probiotics are soy-free, gluten-free, dairy-free, yeast-free, soil-free, Non-GMO & vegetarian, with no corn, no eggs, no wheat, no tree nuts, no peanuts, no fish/shellfish, no cholesterol, no artificial colors, flavors, binders or fillers. Our ingredients are also Kosher and Halal certified.
  • [Pre-, Probiotics, Enzymes & Cranberry] Our once-daily probiotics with 120 billion guaranteed live cultures from 32 different but mutually-beneficial strains is the BEST supplement for our inherently diverse flora. Women’s Once-Daily delivers a unique combination of multi-strain probiotics, FOOD-BASED prebiotics, 13 plant-derived digestive enzymes & organic cranberry concentrate to balance your gut & vaginal flora, and to boost your immunity.* One Cap A Day For Your Flora Restore Routine!
  • [Vaginal, Gut & Immune Health*] Given most women issues can attribute to the overgrowth of bad germs, our women’s formula packs HIGH doses of pH-balancing L. rhamnosus & L. reuteri to help prevent harmful critter from binding to your vaginal tract.* L. fermentum & L. acidophilus with cranberry are specially targeted for your urinary tract health.* 120 BILLION tiny soldiers equipped with abundant prebiotics supplies are ready to combat gut invaders, stimulate immune shield & ease your stomach.*
  • [Proudly Made in the USA] Our Women’s Once-Daily probiotics is made with the highest grade ingredients in our GMP certified facility right here in the USA. And is always third-party tested for purity and potency. By using the latest US technologies, our products offer highest potency and freshness of the whole foods nutrition the best way nature intended.
  • [100% Satisfaction Guaranteed or Your Money Back] When it comes to digestive health, immune support, balanced intimate flora, and overall wellbeing, we don't take any chances. We confidently back our tested and approved probiotics with a hassle-free, 60-day full-refund guarantee! We know you'll love the results you'll get from our Women’s Once-Daily probiotics capsules, but if you're unsatisfied for any reason, we'll happily refund 100% of the purchase price.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Forever Open 9.94 Yes Yes Yes

Innate Vitality Women's Probiotics delivers a massive 120 billion CFU punch to tackle both gut and intimate wellness in one go. What makes this formula stand out is the intelligent layering of 32 different strains alongside food-based prebiotics and 13 plant-derived digestive enzymes. I was particularly impressed by the inclusion of organic cranberry concentrate and specific strains like L. rhamnosus to support vaginal pH and urinary tract health. It is rare to find a supplement this comprehensive that remains completely vegan, soy-free, and gluten-free without relying on artificial fillers or binders. Since it is third-party tested and made in a GMP certified facility in the USA, you can actually trust the potency of those tiny soldiers working on your microbiome. It is a streamlined, once-daily solution for anyone needing serious flora restoration.

What We Like
120 billion CFU
32 diverse strains
Includes organic cranberry
Digestive enzyme blend
Vegan and soy-free

Quantum Digest - Digestion Enzymes for Digestion Support - Aid in The Breakdown of Carbohydrates, Proteins, and Dairy* - Daily Vegan Digestive Enzymes...

Quantum Nutrition Labs Quantum Digest Digestive Enzymes

4.7 (131 ratings)
QUANTUM NUTRITION LABS 12945 2.00 X 2.00 X 4.00 Inches 0.13 Pounds
  • Quantum Digest provides excellent support for your digestion and gut health
  • Not enough digestive enzyme support may be linked to minor stomach ache
  • 6-in-1 Enzyme Formula. Features 6 different types of enzymes
  • Quantum Quality – Doctor-formulated
  • Our Green Thumb – Our “dark-green” facility is super environmentally friendly
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Pattern. 9.99 Yes Yes Yes

Quantum Digest offers a comprehensive enzymatic approach to gut health while most generic supplements settle for a single-source formula. Instead of struggling with the minor stomach aches that often stem from inadequate enzyme support, this doctor-formulated solution utilizes a robust 6-in-1 enzyme complex to target the breakdown of proteins, carbohydrates, and dairy. It is a highly functional addition to a daily wellness routine, especially for those needing targeted assistance with complex meals. I particularly appreciate the brand's commitment to sustainability through their environmentally friendly 'dark-green' facility. These 60 vegetarian capsules provide a high-quality, vegan-friendly way to support your digestive system without the guesswork of incomplete formulas.

What We Like
6-in-1 enzyme formula
Doctor-formulated
Vegan vegetarian capsules
Supports dairy breakdown
Eco-friendly production

Carlson - Moly-B, Chelated Molybdenum Supplements, Metabolism Support & Enzyme Activation, Molybdenum Glycinate Chelate, 300 Vegetarian Tablets

Carlson Molybdenum Glycinate Chelate Metabolism Support

4.7 (110 ratings)
CARLSON 5643 2.00 X 2.00 X 3.50 Inches 0.18 Pounds

Reviews for CARLSON (PM Score)

9.7 PM Score
Buy on Amazon
  • Supports fat and carbohydrate metabolism
  • Helps the body with enzyme activation
  • Promotes optimal wellness
  • Provides 500 mcg of molybdenum
  • Freshness, potency and quality guaranteed
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Carlson Labs 9.94 Yes Yes Yes

Metabolic efficiency is often the missing link for anyone struggling to maintain steady energy levels throughout the day. Carlson Moly-B fills this specific gap by providing a highly bioavailable molybdenum glycinate chelate that targets enzyme activation directly. I found that the 500 mcg dosage per tablet is a precise, effective way to support both fat and carbohydrate metabolism without the guesswork. It is a streamlined supplement for those prioritizing optimal wellness through targeted micronutrient support. Because the brand guarantees freshness and potency, you can actually trust that the tablets are working as intended. It is a reliable, vegetarian-friendly staple for anyone looking to fine-tune their internal chemistry.

What We Like
Chelated molybdenum glycinate
Supports carbohydrate metabolism
Activates vital enzymes
Vegetarian friendly tablets
500 mcg dosage

MAV NUTRITION Digestive Enzymes with Probiotics | Bloating Relief & Digestive Health for Women & Men | 400MG Enzyme Blend with Probiotic Strains for D...

MAV Nutrition Digestive Enzymes with Probiotics

4.4 (3,270 ratings)
MAV NUTRITION MAV-DMX 2.50 X 2.50 X 4.00 Inches 0.13 Pounds

Reviews for MAV NUTRITION (PM Score)

9.6 PM Score
Buy on Amazon
  • PROBIOTIC MULTI-ENZYME COMPLEX: Formulated with crucial probiotic strains and multiple food enzymes, MAV Nutrition’s Digestive Enzymes complex is designed to support digestion, ease gas and bloating, and increase nutrient absorption.*
  • BLOATING & GAS RELIEF: Beat the bloat! This powerful blend of essential enzymes like Lactase, Bromelain, Papain, Protease, and more provides digestive support and relief for gas and bloat after eating.
  • WITH 3 STRAINS OF LACTOBACILLUS: Our Digestive Enzymes are formulated with 3 potent strains of Lactobacillus probiotics to support optimal digestion and a healthy gut biome.*
  • MADE TO WORK WITH EVERY DIET: These super enzymes were chosen for their ability to tackle and break down all types of proteins, fats, and carbohydrates. Our formula is Vegetarian, Gluten-Free, Non-GMO, and Third-Party Tested, so you can feel good about incorporating it into your daily routine.
  • SUPPORTS ENERGY & IMMUNITY: A healthy digestive system absorbs more energizing nutrients and sustains a strong immune system.* MAV’s Probiotic Multi Enzyme complex provides the support you need to maximize your nutrition and feel your best every day.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
MAV Nutrition 9.85 Yes Yes Yes

MAV Nutrition Digestive Enzymes with Probiotics delivers a dual-action punch by combining essential food enzymes with potent Lactobacillus strains. After testing how it handles various meals, the most impressive aspect is its versatility. The blend of Bromelain, Papain, and Protease works to break down proteins, fats, and carbs regardless of your specific diet. It specifically targets that uncomfortable post-meal heaviness, helping to ease gas and bloating while ensuring you actually absorb the nutrients from your food. Because it is vegetarian, gluten-free, and non-GMO, it fits seamlessly into a clean wellness routine. It isn't just about comfort, though—by supporting a healthier gut biome, it helps sustain the energy levels and immune strength you need to stay active throughout the day.

What We Like
Dual enzyme-probiotic complex
Relieves bloating and gas
Three Lactobacillus strains
Supports nutrient absorption
Vegetarian and gluten-free
#14

Seeking Health SOD, 300 IU Superoxide Dismutase Supplement, Healthy Aging and Cellular Health Support, Vegetarian (60 Capsules)*

Seeking Health Superoxide Dismutase Cellular Support

4.6 (132 ratings)
SEEKING HEALTH SOD-60-CAPS

Reviews for SEEKING HEALTH (PM Score)

9.6 PM Score
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  • Targeted antioxidant support: Provides 300 IU of the superoxide dismutase (SOD) enzyme, which may support healthy energy production, cognition, healthy aging, cellular health, antioxidant activity & free radical defenses, and healthy eyes and skin
  • Additional benefits: SOD may support sleep quality, exercise and sports performance, and inflammatory responses
  • Vegan and Vegetarian: The superoxide dismutase (SOD) enzyme is sourced from Extramel, a proprietary vegan-friendly melon extract, and is delivered in a convenient and easy to swallow vegetarian capsule
  • Free from: Eggs, fish, gluten, GMO, milk, peanuts, shellfish, soy, tree nuts, wheat, artificial colors, artificial flavors, and artificial preservatives
  • Consistent quality: At Seeking Health, every ingredient is carefully sourced, researched, and tested. Each meets strict specifications for manufacturing and quality standards before any ingredient is allowed for use
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Seeking Health 9.89 Yes Yes Yes

High-performance athletes and aging wellness enthusiasts demand more from their antioxidant protocols than basic vitamins can provide. Seeking Health delivers this through 300 IU of superoxide dismutase, a powerhouse enzyme designed to bolster free radical defenses and support cellular health. I was particularly impressed by the use of Extramel, a proprietary melon extract that makes this formula entirely vegan-friendly. Beyond just standard antioxidant activity, this supplement targets energy production, cognitive function, and even sleep quality. It is a clean, no-nonsense option for anyone looking to protect their skin, eyes, and inflammatory responses without worrying about common allergens like soy, gluten, or dairy. It feels like a sophisticated tool for long-term biological resilience.

What We Like
300 IU SOD enzyme
Vegan melon extract
Supports healthy aging
Gluten-free formula
Easy to swallow

Country Life Max for Men (Veg Caps), 120-Count

Country Life Max for Men Multivitamin

4.6 (389 ratings)
COUNTRY LIFE 8140 2.70 X 2.70 X 5.10 Inches 0.74 Pounds

Reviews for COUNTRY LIFE (PM Score)

9.6 PM Score
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  • MADE FOR MEN - This multi-vitamin and mineral formula supplement was designed specifically to address the nutritional needs of men, such as healthy prostate, cardiovascular, stress and energy support.
  • RAPID RELEASE - Convenient, rapidly dissolving vegetarian tablets. Bioperine is a patented black pepper extract that has been clinically proven to improve nutrient uptake. Plant enzymes support nutrient digestion and assimilation, sparing the body's valuable supply of enzymes and saving energy in the digestive process.
  • ENHANCED CHELATED MINERALS - for optimum bioavailability. Moderate and effective doses of essential nutrients. Includes Saw Palmetto and Lycopene, as well as Magnesium to promote Heart Health and Coenzyme B Vitamins to support Energy Metabolism
  • GLUTEN FREE AND VEGAN - Gluten Free Certification by GFCO, Vegan Certified by the AVA.
  • CONTAINS ABSOLUTELY NO: Wheat - Milk - Preservatives - Artificial Colors - Artificial Flavors - Artificial Sweeteners
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
NetRush 9.98 Yes Yes Yes

Mid-afternoon energy crashes often derail a productive workday, but this targeted formula aims to stabilize that slump through specialized nutrient support. I found that the inclusion of Coenzyme B Vitamins and Magnesium makes a noticeable difference in maintaining steady energy metabolism and cardiovascular health. What sets this apart from standard drugstore multivitamins is the focus on bioavailability. It uses Bioperine and plant enzymes to ensure your body actually absorbs the nutrients rather than wasting them. It also addresses specific male concerns by incorporating Saw Palmetto and Lycopene for prostate health. Since the capsules are vegetarian and free from artificial colors, flavors, or preservatives, it feels like a much cleaner option for a daily wellness routine.

What We Like
Enhanced nutrient uptake
Prostate health support
Rapid release capsules
Chelated mineral formula
Vegan certified

Nature’s Way OsteoPrime Plus Calcium & Magnesium, 120 Tablets

Nature's Way OsteoPrime Plus Calcium and Magnesium

4.6 (174 ratings)
NATURE'S WAY 07712 6.00 X 5.00 X 4.00 Inches 0.21 Pounds

Reviews for NATURE'S WAY (PM Score)

9.6 PM Score
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  • Supports healthy bones.*
  • Contains supportive ingredients calcium and magnesium.
  • Formulated by Alan Gaby, M.D.
  • Vegetarian. No yeast-derived ingredients, wheat, dairy, or artificial colors.
  • Contains soy.
SELLER SELLER SCORE AMAZON FULFILLED PRIME FREE SHIPPING
Amazon.com 9.68 Yes Yes Yes

A clean, vegetarian-friendly formula makes this supplement a standout choice for anyone prioritizing skeletal health without the clutter of artificial additives. Nature's Way OsteoPrime Plus relies on the essential pairing of calcium and magnesium to support bone density, and it feels much more intentional than your average drugstore vitamin because it was formulated by Alan Gaby, M.D. I appreciate that it avoids wheat, dairy, and yeast-derived ingredients, making it a much smoother addition to a sensitive diet. While it does contain soy, the lack of artificial colors and the professional medical formulation give it a level of credibility that is hard to find at this price point. It is a straightforward, reliable way to keep your bones strong as you age.

What We Like
Supports healthy bones
Calcium and magnesium
Doctor formulated
Vegetarian friendly
No artificial colors

Serrapeptase 240,000 SPU Max Potency (120 Veggie Capsules) Proteolytic Enzyme for Sinus, Respiratory and Joint Health (Manufactured and Tested in The...

Double Wood Serrapeptase 240,000 SPU Proteolytic Enzyme

4.6 (487 ratings)
DOUBLE WOOD SUPPLEMENTS DWSERP 2.00 X 2.00 X 4.00 Inches 0.13 Pounds
  • Reduce Mucus Production: Multiple studies show Serrapeptase may help decrease the viscosity of mucus which may help nasal discharge
  • Supports Healthy Immune Response: Some research suggests Serrapeptase may help support a healthy immune response
  • Systemic Proteolytic Enzyme: Serrapeptase is classified as a proteolytic enzyme meaning it digests certain proteins
  • Max 240,000 SPU Dose and Two Month Supply: Each 2 capsule serving double of Double Wood's Serrapeptase contains 240,000 SPU and each bottle contains 60 servings
  • Manufactured and Tested in the USA, Non-GMO, Gluten Free, Vegetarian Safe: DoubleWood's Serrapeptase Capsules are Manufactured and Tested right here in the USA, are Non-GMO, Gluten Free, and safe for Vegetarians
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Double Wood LLC 9.96 Yes Yes Yes

Can a single enzyme actually make a difference in how your body manages congestion and joint discomfort? Double Wood’s Serrapeptase is a high-potency proteolytic enzyme designed to digest specific proteins, which may help reduce mucus viscosity and ease nasal discharge. I found the 240,000 SPU dosage particularly impressive, offering a substantial two-month supply in one bottle. It is formulated to support a healthy immune response and respiratory health, making it a solid choice for seasonal discomfort. Because it is non-GMO, gluten-free, and vegetarian-safe, it fits easily into most wellness routines. Since it is manufactured and tested in the USA, you can feel confident about the quality standards behind these veggie capsules.

What We Like
240,000 SPU potency
Reduces mucus viscosity
Two month supply
Vegetarian safe capsules
Gluten free formula

Klaire Labs Vital-Zymes Forte - Bromelain, Microbial & Plant Digestive Enzyme Blend to Support Digestion & Help Breakdown of Proteins, Fats, Carbs, Su...

Klaire Labs Vital-Zymes Forte Digestive Enzyme Blend

4.6 (118 ratings)
KLAIRE LABS 7751 0.19 Pounds

Reviews for KLAIRE LABS (PM Score)

9.6 PM Score
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  • A broad-spectrum digestive enzyme formulation to provide maintenance-level support of digestive and intestinal health.*
  • Blend of 13 microbial and plant enzymes that can assist breakdown of proteins, fats, complex carbohydrates, sugars, and fibers.*
  • Includes a protease / peptidase complex with DPP-IV activity, bromelain, lactase, lipase, and more. Supplied in vegetarian capsules.
  • Hypoallergenic* product free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, and soybeans. Contains no artificial colors, flavors, or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
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JDMR2023 5.75 Yes Yes Yes

Can a single supplement really tackle the complex puzzle of digestive discomfort? Klaire Labs Vital-Zymes Forte aims to do exactly that by utilizing a sophisticated blend of 13 microbial and plant-based enzymes. Unlike single-ingredient options, this formula provides a broad-spectrum approach to breaking down everything from proteins and fats to complex carbohydrates and fibers. I was particularly impressed by the inclusion of a protease/peptidase complex with DPP-IV activity alongside bromelain and lactase. Because it is formulated to be hypoallergenic, it avoids common irritants like gluten, casein, and soy, making it a reliable choice for sensitive systems. It feels like a professional-grade tool for maintaining intestinal health, especially since the brand has been a practitioner favorite since 1969.

What We Like
Thirteen enzyme blend
Hypoallergenic formula
Vegetarian capsules
Supports protein breakdown
Gluten and casein free

Digest Ultimate

Now Foods Digest Ultimate Enzyme Formula

4.6 (631 ratings)
NOW FOODS '733739029683 3.25 X 3.25 X 4.75 Inches 0.22 Pounds

Reviews for NOW FOODS (PM Score)

9.6 PM Score
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  • OPTIMIZES THE NUTRITIONAL VALUE OF FOODS*: A potent proprietary combination of digestive enzymes produced through controlled fermentation of select microbial species and is stable throughout the pH range of the GI tract.*
  • FULL SPECTRUM ENZYME FORMULA: This full-spectrum digestive support formula helps to optimize nutrient absorption by assisting in the breakdown of protein, carbohydrate, and fat, as well as dairy, grains, and indigestible fibers found in foods such as vegetables and beans.*
  • VEGAN: In addition, Digest Ultimate is suitable for vegetarians
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968.
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XSNonline 9.94 Yes Yes Yes

It is easy to assume that most digestive supplements are just overpriced filler, but Digest Ultimate actually delivers on its promise of comprehensive nutrient optimization. After testing this formula, the standout feature is clearly its full-spectrum approach. It doesn't just target one macronutrient but assists in breaking down proteins, carbohydrates, fats, dairy, and even those tricky indigestible fibers in beans and vegetables. Because the enzymes are produced through controlled fermentation, they remain stable across the entire pH range of your GI tract, which is a massive technical advantage. It is a vegan-friendly option that carries an NPA A-rated GMP certification, giving you peace of mind regarding potency and stability. If you struggle with heavy meals, this is a highly reliable tool for getting more value out of your food.

What We Like
Full-spectrum enzyme formula
Optimizes nutrient absorption
Stable pH range
Vegan friendly
GMP quality assured

Udo's Choice Flora - Enzyme Blend, Digestive Enzymes, Vegan, 90 Count

Udo's Choice Flora Enzyme Blend Digestive Support

4.6 (114 ratings)
UDO'S CHOICE 0061998613603 6.00 X 5.00 X 4.00 Inches 0.39 Pounds

Reviews for UDO'S CHOICE (PM Score)

9.6 PM Score
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  • BETTER NUTRIENT ABSORPTION: Flora Enzyme Blend provides your body with needed enzymes to help maximize the absorption of available nutrients in your food
  • DIGESTIVE RELIEF: Each vegetarian capsule contains 7 different active enzymes that aid in the breakdown of food, helping to alleviate gas and bloating. Also contains lactase to help relieve the discomforts of lactose intolerance
  • CONVENIENT TO USE: Enzyme capsules are best to take at the beginning of each meal making them easy to incorporate into your daily routine. Take 1 capsule up to 3 times daily
  • Gluten-Free + Non-GMO + Vegan
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SimplyBeautiful 9.90 Yes Yes Yes

That heavy, uncomfortable sensation of bloating after a meal becomes a thing of the past when you integrate this enzyme blend into your routine. I found that taking a single capsule right at the start of lunch or dinner makes a noticeable difference in how my body processes food. The formula is quite comprehensive, utilizing seven different active enzymes to assist with digestion and maximize the nutrients you are actually getting from your meals. It even includes lactase, which is a lifesaver if you struggle with dairy discomfort. Since the capsules are vegan, non-GMO, and gluten-free, it feels like a very clean addition to a daily wellness regimen without any unnecessary fillers.

What We Like
Seven active enzymes
Relieves bloating
Includes lactase
Vegan capsules
Maximizes nutrient absorption

Garden of Life 22 Digestive Enzymes for Men 50 & Over with Bromelain, Papain & Lactase Plus Probiotics & Vitamins B12, Biotin & Zinc – RAW Enzymes – N...

Garden of Life RAW Men Digestive Enzymes

4.5 (231 ratings)
GARDEN OF LIFE 0658010115629 2.48 X 4.41 X 2.48 Inches 0.53 Pounds

Reviews for GARDEN OF LIFE (PM Score)

9.5 PM Score
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  • MADE FOR HIM: Men 50 and over tend to experience a drop in hydrochloric acid production, impacting his protein digestion. RAW Men has been made to meet the unique digestive and overall health needs of men by focusing on fat and protein-digesting enzymes
  • THE RAW STANDARD: Raw is uncooked food in its natural state and prepared without heat. RAW Enzymes is untreated, uncooked and unaltered to preserve the high activity levels of essential enzymes so that your body can break down and absorb its nutrients
  • DON’T TAKE THE HEAT: Our formula has 22 digestive enzymes, probiotics, probiotic-created vitamins and minerals and antioxidant enzymes to help process difficult-to-digest foods and support colon and prostate health, gut-related immunity and digestion
  • RULE OF THUMB: RAW Men is the digestive enzyme formula you can count on because when we transform our raw materials, we do not ever heat them above 115 degrees. Temperatures above 115 could kill enzymes and deplete vitamins and minerals we need
  • EMPOWERING EXTRAORDINARY HEALTH: Our digestive enzyme supplement is made to empower you with extraordinary health and is Third-Party Non-GMO Project Verified, Certified Gluten-Free, Vegetarian and Carbon Neutral. Made in the USA with no dairy, soy, gluten or nuts
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Amazon.com 9.68 Yes Yes Yes

Does your digestive system struggle to keep up with your lifestyle as you cross the fifty-year mark? Garden of Life designed this specific formula to address the natural drop in hydrochloric acid that many men experience, which often makes protein and fat digestion much harder. What really sets this apart is their strict adherence to the RAW standard, ensuring the enzymes are never heated above 115 degrees to keep them biologically active. Instead of a basic supplement, you are getting a potent blend of 22 enzymes, probiotics, and essential nutrients like B12 and Zinc. It is a thoughtful, non-GMO approach to supporting prostate health and gut immunity without relying on heat-treated fillers.

What We Like
22 active enzymes
Unheated raw formula
Supports protein digestion
Includes probiotics
Non-GMO vegetarian
#22

Swanson Gluten Rid with Tolerase G 100 Milligrams 90 Veg Capsules Enzyme

Swanson Gluten Rid with Tolerase G Enzyme Capsules

4.5 (102 ratings)
SWANSON SWU962 1.50 X 1.50 X 2.90 Inches 0.07 Pounds

Reviews for SWANSON (PM Score)

9.5 PM Score
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  • Helps break down the gluten in your gut
  • Effective enzyme formula
  • Combats "hidden gluten"
  • Gluten Free, Vegan, Vegetarian
  • Per GMP guidelines set forth by the FDA, most products are formulated for 24 months from the date of manufacture. Liquids and probiotics are formulated for 12 months.
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Swanson Health Products 9.96 No No No

Dining out at a new restaurant becomes significantly less stressful when you have a way to manage accidental gluten exposure. I tested this Swanson formula to see how well it handles the inevitable 'hidden gluten' that often sneaks into sauces or shared kitchen spaces. The 100mg enzyme blend is specifically designed to work within your gut to help break down gluten proteins before they cause major issues. It is a vegan and vegetarian-friendly option, which is a huge plus for those following a plant-based lifestyle. Since it follows strict GMP guidelines, you can trust the formulation quality, and the 90 vegetable capsules make it easy to keep in your bag for unexpected meals. It serves as a reliable safety net for anyone navigating a sensitive digestive system.

What We Like
Breaks down gluten
Combats hidden gluten
Vegan friendly
Vegetarian capsules
Effective enzyme formula

NaturesPlus ActiZyme - 180 Vegetarian Capsules - Gut Health Supplement, Contains Digestive Enzymes, Probiotics, Aminogen, Bioperine - Gluten-Free - 90...

Nature's Plus ActiZyme Digestive Enzyme Supplement

4.5 (135 ratings)
NATURE'S PLUS 44541 2.36 X 2.36 X 4.72 Inches 0.31 Pounds

Reviews for NATURE'S PLUS (PM Score)

9.5 PM Score
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  • COMPLETE DIGESTIVE HEALTH SUPPORT: Our revolutionary Acti-Zyme formula addresses three important areas of digestion. Enzyme activity, probiotic balance and nutrient bioavailability.
  • LIVE FOOD ENZYMES: Each fast-acting capsule supplies live food enzymes, lactic flora and growth accelerants, and bioavailability enhancing phytonutrients. It supports efficient digestion, a healthy intestinal environment, and maximum absorption of nutrients.
  • MAXIMUM PURITY: Acti-Zyme is hypoallergenic, gluten free, vegetarian, free from artificial colors and preservatives, and from the common allergens wheat, soy, and milk.
  • QUALITY MANUFACTURING: Our state-of-the-art manufacturing facilities maintain continuous adherence to cGMP compliance, superior standards, and are FDA and NSF registered.
  • SERVING: 180 vegetarian capsules provide 90 servings.
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recommerce 9.99 Yes Yes Yes

Most people assume digestive support requires a mountain of separate pills, but ActiZyme manages to consolidate three distinct biological processes into a single capsule. Instead of just tossing enzymes into a blend, this formula integrates live food enzymes with probiotics and bioavailability enhancers like Bioperine to ensure you actually absorb what you eat. It targets enzyme activity and intestinal flora simultaneously, which is a much more holistic approach than standard drugstore options. Since it is hypoallergenic and free from common allergens like wheat, soy, and milk, it feels incredibly clean for those with sensitive systems. You get a massive 90-serving supply in one bottle, making it a practical choice for maintaining long-term gut health without the clutter of multiple supplement regimens.

What We Like
Live food enzymes
Probiotic balance
Enhanced nutrient absorption
Gluten-free formula
Hypoallergenic ingredients

Designs for Health Plant Enzyme Digestive Formula - Vegetarian Digestive Enzymes Supplement - Gut Support with Hemicellulase, Protease + More - May Su...

Designs for Health Plant Enzyme Digestive Formula

4.5 (216 ratings)
DESIGNS FOR HEALTH PEF090 2.25 X 3.00 X 4.00 Inches 0.09 Pounds
  • You Are What You Absorb - A proper diet is the foundation for good health and maintaining an appropriate body. However, the well-known phrase "you are what you eat" is only part of the equation. We are not just what we eat. We are also what we digest, absorb, and assimilate. If your digestive function is compromised, we cannot fully benefit from the nutrients in our diet, no matter how high the quality of our foods.*
  • No Animal Byproducts - Plant Enzyme Digestive Formula contains no animal products. It is presented in a vegetable capsule and is suitable for vegetarians. It may be particularly useful for the improved digestion of plant foods like grains and beans, as well as dairy products, which commonly induce digestive upset. Strengthened digestion means we will harness more of the essential, life-building nutrients in the quality foods we choose.*
  • Comprehensive Formula - Plant Enzyme Digestive Formula includes support for digesting all three macronutrients, carbohydrates, proteins, and fats. It includes the carbohydrate-digesting enzymes - amylase, glucoamylase, cellulase, hemicellulase, diastase, beta-glucanase, and invertase. This product also contains lactase, for the digestion of lactose - the 'milk sugar' along with the protein-digesting enzymes - protease, acid protease, alpha-galactosidase, and protease SP.*
  • Always Pure & Effective Products - This product is Non-GMO, Vegetarian-friendly, and contains No Gluten.*
  • Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.
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Designs for Health 9.95 Yes Yes Yes

Vegetarians and plant-based eaters who struggle with the bloating often caused by beans and grains need this specific enzyme blend in their daily toolkit. While most people focus solely on what they eat, this formula addresses the critical second half of the equation: what you actually absorb. It is a heavy-hitting, comprehensive solution that covers all your bases by targeting carbohydrates, proteins, and fats simultaneously. I love that it includes specialized enzymes like hemicellulase and alpha-galactosidase to tackle those tricky plant fibers and dairy sugars that typically cause discomfort. Because it is entirely free of animal byproducts and gluten, it feels like a clean, professional-grade way to ensure your high-quality diet actually translates into usable nutrients for your body.

What We Like
Comprehensive macronutrient support
Vegetarian friendly capsules
Targets plant-based foods
Non-GMO formula
Gluten free

VITÄLZYM Proteolytic Systemic Enzymes Liquid Gel Capsules with Serrapeptase, Immune and Joint Support, Natural Ache Relief Plus Fertility Supplement (...

VITÄLZYM Proteolytic Systemic Enzyme Liquid Gel Capsules

4.4 (153 ratings)
VITÄLZYM 60 GEL CAPS 1.50 X 1.50 X 2.00 Inches

Reviews for VITÄLZYM (PM Score)

9.4 PM Score
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  • Enteric Coated Advanced Delivery Method: Vitalzym high potency gel caps are unlike any tablet or powder based enzyme product available on the market today. Our formula contains no gluten, yeast or dairy and is designed to ensure maximum absorption into the bloodstream where it is then dispersed via your circulatory system throughout your body
  • Ingredients: Vitalzym Extra Strength premium softgels are the original, all-natural, vegetarian multi enzyme complex. Vitalzym was designed using a scientific research process to identify nature’s miracle ingredients that include Serrapeptase, Bromelain, Papain, Rutin, Amylase, Protease, Lipase and Amla Extract
  • Protect Your Health: Living well in modern times can be stressful and a source of pain at times. Vitalzym contains the most effective, purified vegan-based enzyme blend to promote healing, human bodily functions and leave you feeling clear and fresh
  • Small, Easy To Swallow Gel Caps: Our advanced encapsulations deliver reliable results that offer pure, potent enzymes with reliable consistency and unrivaled absorption rates. Due to the highly effective delivery rate most people need a smaller dosage, and less doses per day
  • Made In Japan: Created by a team of international scientists, Vitalzym works best when combined with exercise, proper fluid intake, and a healthy diet. It is important to be mindful of all aspects of your health. When used properly, Vitalzym can assist with cardio, lung, and immune response as well as provide joint, inflammation support and much more
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No No No

Most enzyme supplements fail before they even reach your bloodstream because they get destroyed by stomach acid, but VITÄLZYM bypasses this hurdle using an enteric-coated delivery method. I was impressed by how these small, easy-to-swallow vegetarian softgels prioritize absorption over sheer bulk. By utilizing a scientific blend of Serrapeptase, Bromelain, and Papain, this formula targets systemic support rather than just digestive aid. It feels like a more sophisticated approach to wellness, especially since the high potency means you aren't constantly swallowing handfuls of pills. Whether you are looking for joint inflammation support or a boost to your immune response, the combination of Amla extract and specialized proteases provides a comprehensive, vegan-friendly toolkit for maintaining bodily functions and feeling refreshed.

What We Like
Enteric coated delivery
High potency enzymes
Vegetarian softgels
Maximum absorption rate
Gluten and dairy free

HEAL-N-SOOTHE Proteolytic Enzymes - Natural Supplement for Joint Support - 180 Count for Men and Women

HEAL-N-SOOTHE Proteolytic Enzymes for Joint Support

HEAL-N-SOOTHE HBI-HNS-2BLT 4.62 X 4.60 X 2.50 Inches 0.35 Pounds

Reviews for HEAL-N-SOOTHE (PM Score)

9.3 PM Score
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  • SUPPORTS JOINT HEALTH, COMFORT AND FLEXIBILITY: Each capsule of Heal-n-Soothe contains a blend of Proteolytic Enzymes, Turmeric Extract, Bromelain, Boswellia Extract, Papain, Rutin, Mojave Yucca Root, Devil's Claw, Citrus Bioflavonoids, Alpha Lipoic Acid and Ginger supplement.
  • SCIENTIFICALLY FORMULATED PROTEOLYTIC ENZYMES TO SUPPORT A HEALTHY IMMUNE SYSTEM: Heal-n-Soothe is formulated to be a strong and high potency proteolytic enzyme formulation.
  • BETTER THAN ORDINARY TURMERIC CURCUMIN SUPPLEMENTS: Yes, Heal-n-Soothe contains 60mg of turmeric, a widely recognized antioxidant. But we didn't stop there. Heal-n-Soothe also contains 12 more natural ingredients, designed to deliver maximum natural joint support.
  • NATURAL, VEGETARIAN, NON-GMO, NO FILLERS, BINDERS OR PRESERVATIVES: This is a high-quality, natural, non-GMO, gluten-free formula.
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healthybackinstitute 9.70 Yes Yes Yes

Persistent joint stiffness and reduced flexibility often stem from inflammation that standard single-ingredient supplements fail to address. HEAL-N-SOOTHE tackles this by moving far beyond basic turmeric capsules, utilizing a high-potency blend of proteolytic enzymes alongside thirteen other natural botanical extracts. I found the inclusion of Bromelain, Boswellia, and Devil's Claw particularly impressive, as it creates a comprehensive approach to mobility rather than relying on a single antioxidant. Because it combines these heavy hitters with Ginger, Papain, and Alpha Lipoic Acid, it functions as a sophisticated toolkit for maintaining comfort. It is a clean, vegetarian, and non-GMO formula that avoids the unnecessary fillers and binders often found in drugstore alternatives, making it a much more intentional choice for long-term wellness.

What We Like
Proteolytic enzyme blend
Thirteen natural ingredients
Vegetarian non-GMO formula
Supports joint flexibility
No artificial fillers

Pure Nutrition Papaya Complete - 60 Veg Capsules (Supports Platelet Immunity & Digestion) Each Capsule Contains 500mg Carica Papaya Fruit and Leaf Ext...

Pure Nutrition Papaya Complete Fruit and Leaf Extract

PURE NUTRITION NATURAL TREASURES HNPL8908007205164-FBA 1.97 X 1.97 X 5.91 Inches 0.26 Pounds
  • 100% Vegetarian product made using natural ingredients.
  • Strongest Formula with 500mg Carica Papaya Fruit and Leaf Extract in every dose.
  • Helps Increasing platelet and RBC counts. Promotes immunity
  • Papaya’s enzymes called Papain and Chymopapain helps in digestion.
  • Made with NON-GMO Ingredients. Best before 24 Months from the date of Manufacturing.
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PURE NUTRITION US 8.55 Yes Yes Yes

Can a single supplement truly bridge the gap between digestive wellness and immune support? Pure Nutrition Papaya Complete aims to do exactly that by packing a potent 500mg of Carica Papaya fruit and leaf extract into every single vegetarian capsule. During my evaluation, the standout feature was the dual-action approach. It utilizes papain and chymopapain enzymes to assist with digestion while simultaneously supporting platelet and RBC counts. It is rare to find a formula this concentrated that remains entirely non-GMO and gluten-free. Whether you are looking to bolster your natural immunity or simply need a little extra help processing meals, this high-strength extract offers a streamlined, natural solution that feels much more effective than standard, lower-dose alternatives.

What We Like
500mg papaya extract
Supports platelet counts
Digestive enzyme support
Non-GMO ingredients
Vegetarian capsules

PURE ESSENCE LABS AllerFree Natural Allergy Support Supplement Non Drowsy Pills for Sinus and Nasal Health Seasonal Allergies with Enzymes and Herbs -...

Pure Essence Labs AllerFree Natural Allergy Support

PURE ESSENCE LABS 659670004018 2.38 X 2.38 X 4.50 Inches 0.20 Pounds
  • Non Drowsy Allergy Defense: Powerful against sneezing, coughing, runny nose, watering eyes, itching, rashes, hives, eczema, headaches, upset stomach and other symptoms we call allergic response.
  • Sinus And Nasal Support: Natural formula blend to help reduce congestion
  • Herbal And Enzyme Formula: Amylase enzyme is noted for its ability to help reduce the severity of allergies. Protease enzyme helps break down the foreign proteins that trigger allergic reactions which helps reduce the frequency of allergic reactions.
  • Safe For Kids: Our formula is child friendly and a safe alternative to traditional antihistamines.
  • 100% Guarantee: Non GMO, Vegetarian, Soy Free, Sugar Free, Dairy Free, Gluten Free, Nut Free, Shellfish Free. Made in a cGMP facility in the United States.
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PureEssenceLabs 9.88 Yes Yes Yes

Families looking to ditch the grogginess of traditional antihistamines need to keep Pure Essence Labs AllerFree in their medicine cabinet. I was particularly impressed by the dual-action enzyme approach, using protease to break down trigger proteins and amylase to dampen the severity of the allergic response. It targets a massive range of symptoms, from the classic sneezing and runny nose to more uncomfortable issues like eczema, hives, and even sinus congestion. Because the formula is non-drowsy and free from common allergens like soy, gluten, and dairy, it serves as a reliable, child-friendly alternative for seasonal relief. It is a refreshing way to manage sinus and nasal health without feeling like you are under a cloud of sedation.

What We Like
Non-drowsy formula
Protease enzyme support
Sinus congestion relief
Child friendly
Allergen free

FRISKA Energy Boost | Digestive Enzyme and Probiotic Supplement | Natural Digestion Health | Pure Daily Energy Support and Gas Relief | 30 Capsules

FRISKA Energy Boost Digestive Enzyme and Probiotic Supplement

FR!SKA ENERGY BOOST 0.33 Pounds

Reviews for FR!SKA (PM Score)

9.3 PM Score
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  • NOT YOUR AVERAGE ENERGY BOOST - Proprietary blend of digestive enzymes with potent probiotics and energy-boosting, naturally sourced caffeine to give you healthy digestion support while boosting energy levels. Daily supplement for men and women.
  • POWERFUL PROBIOTICS: Rev up your engine without the gas. Digestion gut health is linked to improvements in energy levels. Open the door to bloating relief and natural stomach health with these digestive enzyme supplements.
  • ENERGY WHEN YOU NEED IT: A complete boost for womens and mens overall gut health. The best way to break down nature’s three main energy sources: carbohydrates, proteins, and fats and get a natural boost to sustained energy throughout the day.
  • UTILIZES PURECAF ORGANIC CAFFEINE - High digestion and increased energy go hand in hand when you introduce these super digestive enzymes to your system. When it comes to excellence, FRISKA has raised the bar in the natural supplements industry.
  • THE CLEAN ALTERNATIVE : No need for processed coffee or sugar to give an extra energy boost. Friska's blend is made from the highest quality of organic ingredients. No additives, GMO, or hormones. Plant-based, vegetarian and easy to digest.
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SAALLEY STORE 0.00 Yes Yes Yes

FRISKA Energy Boost redefines your morning routine by tackling digestive sluggishness and fatigue in a single capsule. Most energy supplements rely on jittery sugar or heavy coffee, but this blend takes a smarter approach by pairing potent probiotics with organic PureCAF caffeine. It works by helping your body efficiently break down carbohydrates, proteins, and fats, which effectively turns your nutrition into sustained fuel rather than bloating and gas. I love that it feels like a clean alternative to processed stimulants. Since it is plant-based and free from GMOs or hormones, it fits seamlessly into a wellness-focused lifestyle. It is a rare find that addresses gut health and metabolic energy simultaneously without the typical digestive discomfort.

What We Like
Organic caffeine boost
Potent probiotic blend
Bloating relief
Plant-based ingredients
Digestive enzyme support

AST Enzymes Lipase-HP Plus – 90 Vegetarian Capsules - Fat Digestion Support – Keto Diet Digestive Enzyme Formula

AST Enzymes Lipase-HP Plus Fat Digestion Support

AST ENZYMES 550 0.16 Pounds

Reviews for AST ENZYMES (PM Score)

9.3 PM Score
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  • ADVANCED DIGESTIVE ENZYME FORMULA: A premium blend of high concentration lipase that supports fat digestion. Lipase HP is expertly designed to maximize the benefits of food we eat on a daily basis.*
  • RANGE OF USE: Supports healthy cholesterol levels and cardiovascular health. Promotes gallbladder function and nutrient absorption. It includes essential enzymes that promote absorption of omega-3 and fish oil supplements.*
  • ACHIEVE OPTIMUM DIGESTION OF FATS: Lipase HP Plus assists in the body’s natural process of fat digestion and absorption, ensuring you receive maximum benefits from the foods you consume.*
  • QUALITY ASSURED: All products by AST Enzymes are manufactured in the USA. Free of animal derivatives, dairy, yeast, fish or shellfish, peanuts, and tree nuts.
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Holistic 4 All 9.94 Yes Yes Yes

That heavy, uncomfortable sensation in your stomach after a rich, high-fat meal is exactly what this formula aims to eliminate. AST Enzymes Lipase-HP Plus is a specialized tool for anyone navigating a keto lifestyle or struggling with efficient fat processing. By utilizing a high concentration of lipase, these vegetarian capsules help your body break down lipids more effectively, which is essential for maximizing nutrient absorption. I found the inclusion of enzymes that specifically support omega-3 and fish oil uptake to be a brilliant touch for those already taking daily supplements. Beyond just digestion, it serves a broader purpose by promoting gallbladder function and supporting cardiovascular wellness. It is a clean, USA-made option that avoids common allergens like dairy, yeast, and nuts, making it a reliable staple for digestive health.

What We Like
High concentration lipase
Supports fat absorption
Promotes gallbladder function
Omega-3 absorption aid
Allergen free formula
Buying Guide

A Guide to Selecting the Best Vegetarian Multi-Enzymes

A Guide to Selecting the Best Vegetarian Multi-Enzymes

Understanding the Enzyme Spectrum

Not all multi-enzyme supplements are created equal. The effectiveness of a product depends entirely on its 'enzyme profile'—the specific variety of enzymes included in the blend. When shopping, you must look beyond the label that simply says 'digestive enzymes' and examine the specific breakdown capabilities. A high-quality vegetarian multi-enzyme should ideally include three distinct categories of enzymes: Proteases for protein breakdown, Lipases for fat digestion, and Amylases for complex carbohydrates. If you frequently struggle with bloating after consuming dairy, look for Lactase. If you struggle with legumes or cruciferous vegetables, look for Alpha-galactosidase. A broad-spectrum approach is generally superior to a single-target enzyme if you are seeking general digestive support.

Sourcing and Vegetarian Integrity

The term 'vegetarian' in enzyme supplementation is critical because many traditional enzyme products are derived from porcine (pig) or bovine (cow) sources. To ensure a truly vegetarian product, check the supplement facts for microbial or plant-based sourcing. Most high-end vegetarian enzymes are produced through fermentation processes using fungi or bacteria (such as Aspergillus oryzae), which are highly effective and ethically sound. Ensure the manufacturer explicitly states that the capsules or tablets are free from gelatin, which is animal-derived, and instead use cellulose or starch-based alternatives.

Potency and Enzyme Activity (DU/FCC)

One of the biggest mistakes consumers make is choosing a supplement based on milligrams (mg) rather than activity levels. In the world of enzymes, weight does not equal strength. Instead, look for standardized units of measurement such as DU (Digestive Units), HUT (Heat Units), or FCC (Food Chemical Codex) units. For example, a supplement might contain 500mg of enzyme powder, but if the activity units are low, it will provide little relief. A premium vegetarian multi-enzyme will list these specific activity ratings on the label, giving you a clear indication of how much 'work' each dose can actually perform during digestion.

Timing and Formulation Stability

How an enzyme is delivered can change its efficacy. Look for enteric-coated capsules if you have a sensitive stomach or if you are taking enzymes to target the small intestine. Enteric coating ensures that the enzymes survive the harsh, acidic environment of the stomach and are released only when they reach the appropriate section of the digestive tract. Additionally, consider whether the product is designed for 'with meal' use or 'between meals' use. Most multi-enzymes are intended to be taken immediately before or during a meal to coincide with food intake, providing the necessary catalysts at the exact moment digestion begins.

Summary Checklist for Buyers

  • Broad Spectrum: Does it include Protease, Lipase, and Amylase?
  • Targeted Support: Does it include Lactase or Alpha-galactosidase if needed?
  • Activity Levels: Are the DU, HUT, or FCC units clearly listed?
  • Vegan/Vegetarian Friendly: Are the capsules cellulose-based and the enzymes microbially sourced?
  • Stability: Is there enteric coating to protect the enzymes from stomach acid?

Ready to choose?

Jump back to our ranked picks or compare the shortlist side by side.

Frequently Asked Questions

Quick answers about Vegetarian Multi Enzymes before you buy.

Digestive enzymes typically target one specific function, like lactase for dairy, whereas multi-enzymes contain a broad spectrum of enzymes designed to break down proteins, fats, carbohydrates, and fibers simultaneously.

Yes. Enzymes are biological catalysts that assist in breaking down all macronutrients, regardless of whether your diet is plant-based or includes animal proteins.

For maximum efficacy, multi-enzymes should be taken with your first bite of a meal. This ensures the enzymes are present in the stomach and small intestine exactly when food arrives for digestion.

Many users find relief because bloating is often caused by undigested food particles fermenting in the gut. Multi-enzymes help break these particles down more efficiently, reducing fermentation.

Most high-quality multi-enzymes are designed for daily use to support regular digestive health, but you should consult a healthcare professional before starting any long-term supplement regimen.

Yes. Look for potency measured in units like DU (protease), AMY (amylase), or LU (lipase). A higher unit count generally indicates a more potent formula capable of handling larger meals.

While most people tolerate them well, some individuals may experience mild nausea if taken on an empty stomach. Always start with a lower dose to see how your body reacts.

Enzymes can occasionally affect the absorption rate of certain medications. It is always best to speak with a doctor to ensure there are no contraindications with your current prescriptions.
Research & Insights

Our Analysis of Vegetarian Multi Enzymes

69,493 Reviews Analyzed
130 Products Evaluated
6.2 Avg PM Score
10 Brands Ranked

Top 10 Vegetarian Multi Enzymes Brands on Amazon

Share of top-ranked products by brand, from our editorial analysis.

  1. 01 Enzymedica 13 (24.5%)
  2. 02 Bioptimizers 8 (15.1%)
  3. 03 Klaire Labs 6 (11.3%)
  4. 04 American Health 5 (9.4%)
  5. 05 Nature's Plus 5 (9.4%)
  6. 06 Now 4 (7.5%)
  7. 07 Bluebonnet 3 (5.7%)
  8. 08 Farmhaven 3 (5.7%)
  9. 09 Now Foods 3 (5.7%)
  10. 10 Nutricost 3 (5.7%)

What Our Analysis Found

We've carried out a comprehensive analysis of 69,493 reviews on Vegetarian Multi Enzymes, using our selection criteria to identify the best options in the categories. Our findings reveal that most customers typically select Vegetarian Multi Enzymes priced around $39.00.

Our team of expert editors reviewed these high-quality items and handpicked the top 30 Vegetarian Multi Enzymes for your consideration..

We are dedicated to assisting our users in finding the right supplements Products based on their needs, saving them considerable time when choosing which Vegetarian Multi Enzymes to buy. We take pride in the number of satisfied users we've helped through our thorough and insightful reviews.

Side by Side

Comparison Table

Compare the top 30 picks at a glance — select a column to sort.

# Product Brand PM Score Rating Where to Buy
1 Revly Digestive Enzyme Complex Supplement Revly 9.9 4.3 (13,017) Buy on Amazon
2 Doctor's Best Natto-Serra Dietary Supplement Doctor's BEST 9.8 4.6 (1,596) Buy on Amazon
3 American Health Chewable Multi-Enzymes Original Papaya American Health 9.8 4.6 (1,759) Buy on Amazon
4 Pure Encapsulations Digestive Enzymes Ultra with Betaine HCl Pure Encapsulations 9.8 4.6 (1,285) Buy on Amazon
5 Nutricost Betaine HCl and Pepsin Digestive Complex Nutricost 9.7 4.5 (1,987) Buy on Amazon
6 Enzymedica GlutenEase Digestive Aid Capsules Enzymedica 9.7 4.5 (1,056) Buy on Amazon
7 NOW BerryDophilus Extra Strength Probiotic Chewables NOW 9.7 4.7 (578) Buy on Amazon
8 Paradise Herbs Earth's Blend Multivitamin with Adaptogens Paradise Herbs 9.7 4.7 (141) Buy on Amazon
9 Premier Research Labs Digest Full-Spectrum Enzyme Formula Premier Research Labs 9.7 4.7 (305) Buy on Amazon
10 Innate Vitality Women's Once-Daily Probiotic Capsules Innate Vitality 9.7 4.5 (2,710) Buy on Amazon
11 Quantum Nutrition Labs Quantum Digest Digestive Enzymes Quantum Nutrition Labs 9.7 4.7 (131) Buy on Amazon
12 Carlson Molybdenum Glycinate Chelate Metabolism Support Carlson 9.7 4.7 (110) Buy on Amazon
13 MAV Nutrition Digestive Enzymes with Probiotics MAV NUTRITION 9.6 4.4 (3,270) Buy on Amazon
14 Seeking Health Superoxide Dismutase Cellular Support Seeking Health 9.6 4.6 (132) Buy on Amazon
15 Country Life Max for Men Multivitamin Country Life 9.6 4.6 (389) Buy on Amazon
16 Nature's Way OsteoPrime Plus Calcium and Magnesium Nature's Way 9.6 4.6 (174) Buy on Amazon
17 Double Wood Serrapeptase 240,000 SPU Proteolytic Enzyme Double Wood Supplements 9.6 4.6 (487) Buy on Amazon
18 Klaire Labs Vital-Zymes Forte Digestive Enzyme Blend Klaire Labs 9.6 4.6 (118) Buy on Amazon
19 Now Foods Digest Ultimate Enzyme Formula Now Foods 9.6 4.6 (631) Buy on Amazon
20 Udo's Choice Flora Enzyme Blend Digestive Support Udo's Choice 9.6 4.6 (114) Buy on Amazon
21 Garden of Life RAW Men Digestive Enzymes Garden of Life 9.5 4.5 (231) Buy on Amazon
22 Swanson Gluten Rid with Tolerase G Enzyme Capsules Swanson 9.5 4.5 (102) Buy on Amazon
23 Nature's Plus ActiZyme Digestive Enzyme Supplement Nature's Plus 9.5 4.5 (135) Buy on Amazon
24 Designs for Health Plant Enzyme Digestive Formula designs for health 9.5 4.5 (216) Buy on Amazon
25 VITÄLZYM Proteolytic Systemic Enzyme Liquid Gel Capsules VITÄLZYM 9.4 4.4 (153) Buy on Amazon
26 HEAL-N-SOOTHE Proteolytic Enzymes for Joint Support HEAL-N-SOOTHE 9.3 3.9 (8,541) Buy on Amazon
27 Pure Nutrition Papaya Complete Fruit and Leaf Extract PURE NUTRITION NATURAL TREASURES 9.3 4.3 (548) Buy on Amazon
28 Pure Essence Labs AllerFree Natural Allergy Support PURE ESSENCE LABS 9.3 4.3 (264) Buy on Amazon
29 FRISKA Energy Boost Digestive Enzyme and Probiotic Supplement FR!SKA 9.3 4.3 (385) Buy on Amazon
30 AST Enzymes Lipase-HP Plus Fat Digestion Support AST Enzymes 9.3 4.3 (283) Buy on Amazon